What Is Hyaluronic Acid (HA)? Read the Label in 5 Minutes

In short
- HA helps bind and retain water in skin. [1]
- Sodium Hyaluronate is a salt form of HA. [2]
- Check the product category and directions before choosing. [4]
Understanding HA
Thai shoppers often call it “ไฮยา” (hiya). HA is a glycosaminoglycan found in skin, with the ability to bind and retain water. [1]
Start with the ingredient name, then check what kind of product you are holding. Look beyond the HA wording on the front of the box.
Names to recognise
| Ingredient name | Meaning |
|---|---|
| Hyaluronic Acid | The acid form of HA. [2] |
| Sodium Hyaluronate | The sodium salt of HA. [2] |
| Hydrolyzed Hyaluronic Acid | HA whose polymer chains have been shortened. [2] |
Scroll the table →
These names refer to related forms of HA, each conveying something different. Use the table as a starting point. [2]
Some labels also give the molecular size. The review reports that in topical formulas HA below 100 kDa can penetrate the skin, and that the larger the molecule, the more viscous the solution. [2] In our range, Aquatic HA lists high-molecular-weight HA of about 1.5 MDa; it is a procedure product, not a topical serum.
- Record the full ingredient names, including unfamiliar ones.
- Ask the manufacturer for formulation details if you need the concentration.
Read concentration without guessing results
Under U.S. cosmetic labelling rules, ingredients generally appear in descending order of quantity, but those at 1% or less may appear in any order. Position alone therefore cannot give an exact percentage. [3]
HA plays a role in retaining water; that function does not establish the performance of a whole serum. [1] Before comparing HA serums, ask for formulation details and evidence for the finished product rather than judging by ingredient order alone.
Check the intended use separately
Even cross-linked HA has been studied in topical formulations. An ingredient name or the word “cross-linked” does not establish that a product is suitable for injection. [2]
Injectable products, including fillers and injectable skin boosters, must be used by a licensed doctor in a licensed clinic. [6] The U.S. FDA describes filler injection as a medical procedure and advises against self-injection. [5] The doctor chooses the product and determines its use after an assessment.
The U.S. FDA warns that unintended filler injection into a blood vessel can cause tissue death, blindness, or stroke. [5] Before a procedure, ask your doctor to explain the intended use and risks of the proposed product.
Check the label before use
Thai FDA recommends checking the Thai-language label for the cosmetic’s name and type, ingredients, directions, manufacturer or importer, net contents, batch number, manufacturing or expiry date, and notification number. [4]
- Read and follow the formula’s directions and warnings. [4]
- Keep photographs of the packaging and label for questions to the manufacturer or doctor.
- Stop using the cosmetic if you notice an abnormal reaction, as Thai FDA advises. [4]
FAQ
What is hyaluronic acid?
HA is a substance found in skin that binds water, linking it to skin moisture. [1]
What does “ไฮยาลูรอน” mean?
Here, the Thai term refers to HA. Sodium Hyaluronate on a label means its sodium salt form. [2]
What does hyaluronic acid help with?
Its key role is binding and retaining water in skin. [1] When choosing a formula, ask about evidence for the finished product too.
What does HA do for skin?
It contributes to skin moisture. [1] Thai FDA describes cosmetics as providing temporary external care, so a serum should not be expected to permanently change skin structure. [4]
When should I apply hyaluronic acid?
Follow the serum’s label directions, consistent with Thai FDA advice to read and follow instructions and warnings. [4] If you also use a prescribed topical medicine, bring the product names to your doctor and ask about application order.
This information is general knowledge and does not replace a doctor's advice. Every procedure should be done by a licensed doctor.
References
- Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology. 2012;4(3):253–258. https://pmc.ncbi.nlm.nih.gov/articles/PMC3583886/Back to text
- Zanchetta C, Scandolera A, Reynaud R. Hyaluronic Acid in Topical Applications: The Various Forms and Biological Effects of a Hero Molecule in the Cosmetics Industry. Biomolecules. 2025;15(12):1656. https://pmc.ncbi.nlm.nih.gov/articles/PMC12731180/Back to text
- U.S. Food and Drug Administration. Summary of Cosmetics Labeling Requirements. FDA. Accessed 2026. https://www.fda.gov/cosmetics/cosmetics-labeling-regulations/summary-cosmetics-labeling-requirementsBack to text
- สำนักงานคณะกรรมการอาหารและยา. รักต้องเช็ก ! อย. เตือนนักชอปเครื่องสำอางรับวาเลนไทน์ ระวังของปลอม เสี่ยงหน้าพัง. อย. 2569 (2026). https://kbs.fda.moph.go.th/news/new024Back to text
- U.S. Food and Drug Administration. Dermal Fillers (Soft Tissue Fillers). FDA. Accessed 2026. https://www.fda.gov/medical-devices/aesthetic-cosmetic-devices/dermal-fillers-soft-tissue-fillersBack to text
- สำนักงานคณะกรรมการอาหารและยา. ตำรวจสอบสวนกลางร่วม สบส. และ อย.เปิดยุทธการ “หยุดเถื่อน” ปราบหมอปลอมหลอกจิ้มหน้า ตรวจค้น 8 จุด. ศรป. 2565 (2022). https://cemc.fda.moph.go.th/press-release/pr-10Back to text
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