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Hyalase · South Korea

Hyalase (Korea) Imported

BMI hyaluronidase, 1,500 IU; ten vials per box

฿1,540
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Genuine imported stock, lot-checked before shipping
EMS delivery in Thailand 60 THB, dispatched once payment is confirmed
Product warranty

Record an unboxing video every time, from before you open the parcel until it is unpacked, in one uncut take. Without the video, no claim can be accepted.

You can claim

  • A product that arrives broken, damaged or missing
  • The wrong product, still unopened
  • An opened product, only when the item inside is cracked or broken

No claim

  • An opened product in normal condition
  • More than 7 days after delivery without an unboxing video

Benefits of Hyalase (Korea)

  • Dissolves unwanted hyaluronic acid filler
  • Corrects lumpy or uneven filler
  • Fine-tunes filler that looks unnatural

Results vary from person to person

What is Hyalase (Korea)?

Hyalase is a hyaluronidase injection from BMI KOREA Co., Ltd. of South Korea, in a box printed BM Hylunidase.

In short

  • Each box holds 10 vials of 1,500 IU per 1 mL. IU (International Unit) measures enzyme activity, not weight.
  • Only a licensed doctor chooses, mixes and injects it, because the drug is a protein that can cause an allergic reaction.
  • The name Hyalase is also used for a 1500 I.U. hyaluronidase registered in the UK by Wockhardt UK, a different product from BMI's, so check for BM Hylunidase and the maker's name on the box.

Hyaluronidase and fillers

A hyaluronic acid filler may need correcting after a complication such as over-injection, uneven spread or a blocked blood vessel. Doctors use hyaluronidase to break down this type of filler.

A 2025 study in the Journal of Cosmetic Dermatology reports that the effect depends on the filler type, the concentration and the way the enzyme is given. Biphasic fillers break down faster than monophasic ones, and injecting into the filler itself works better than treating the skin surface. The type, amount and timing are therefore for the doctor to judge case by case.

Risks and what to tell the doctor

Hyaluronidase is a protein and can cause allergic reactions, especially at high amounts. The 2025 study advises doctors to have antihistamines and steroids ready, and people with a history of allergy may need preparation before the drug is given.

Anyone considering treatment should tell the doctor about drug allergies, current medicines, and the type, brand, area and date of any filler injected before, so the doctor can decide for their own case.

About the maker, BMI KOREA

BMI KOREA Co., Ltd. was founded in 2005 in South Korea and bought a GMP plant in the Hyangnam pharmaceutical complex in Hwaseong. It now has plants in Jeju and Cheongju. The company says it does business with countries in Europe, the Middle East, Africa, Asia (Thailand included) and the Americas.

Its pharmaceutical product pages list two hyaluronidase products, Hirax Inj. and BM Hyrunidase Inj. The second matches the Hyalase box.

Frequently asked questions

What is hyaluronidase?

It is an enzyme that breaks down hyaluronic acid, which is a different substance. Hyaluronic acid is found in body tissue and in some fillers. Once it is broken down, the tissue becomes less viscous and other substances pass through more easily. The human body makes five active forms; the medicine is produced separately.

What does hyaluronidase do?

In medicine it helps other drugs spread and pass through tissue faster, for example with local anaesthetic in eye surgery, in fluids given under the skin, and when some drugs leak out of a blood vessel. The maker, BMI, says it helps drugs injected under the skin or into muscle, and local anaesthetics, pass through tissue, and helps excess fluid and pooled blood in tissue to be reabsorbed.

Can hyaluronidase dissolve every kind of filler?

No. It breaks down only hyaluronic acid fillers; other types are not broken down. Anyone who has had filler should tell the doctor which type and brand it was.

What is the hyaluronidase used in medicine made from?

Of the hyaluronidases approved in the United States, three are extracted from animals and one is recombinant. Products from different companies can therefore differ, so read the leaflet that comes with the product.

How much is Hyalase / BM Hylunidase?

The price depends on the model and the quantity.

References

  1. BM Hyrunidase Inj. (Hyaluronidase) product information. BMI KOREA Co., Ltd. bmikr.co.kr/en/blog/portfolio-item/%eb%b9%84%ec%97%a0%ed%9e%88%eb%a3%a8%eb%8b%88%eb%8b%a4%ec%a0%9c%ec%a3%bc/(opens in a new tab)
  2. About us (company history, plants and offices). BMI KOREA Co., Ltd. bmikr.co.kr/en/company/(opens in a new tab)
  3. Hyaluronidase. Wikipedia en.wikipedia.org/wiki/Hyaluronidase(opens in a new tab)
  4. How Should We Use Hyaluronidase for Dissolving Hyaluronic Acid Fillers?. Journal of Cosmetic Dermatology (Hong et al.) (2025) pmc.ncbi.nlm.nih.gov/articles/PMC11733830/(opens in a new tab)
  5. Hyalase 1500 I.U. Powder for Solution for Injection/Infusion (SmPC). electronic medicines compendium (emc), Wockhardt UK Ltd (2015) medicines.org.uk/emc/medicine/7315/spc(opens in a new tab)

This information is for general knowledge and does not replace a doctor's advice. Every procedure should be performed by a licensed doctor in a medical facility.

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