NC 135HA Thai label

FILLMED presents NCTF 135 HA as one of its three product groups. The others are ART FILLER, an injectable filler range, and SKIN PERFUSION, skincare for use before and after procedures.

The company says it distributes through a network in more than 80 countries and runs a multi-level traceability system; a practitioner can verify authenticity from a QR code on the manufacturer's packaging.

In February 2025 FILLMED announced that the bottle format of NCTF 135 HA had received MDR certification under European Regulation (EU) 2017/745, the rulebook for medical devices.

The maker describes injection into the skin as small micro-papules with a needle or a cannula. It names multipuncture and retrotracing techniques, and says mesotherapy devices such as a mesogun or a roller can also be used. The areas named are the face, neck and upper chest.

The doctor sets each person's plan after an assessment, checks the expiry date before every use, and never reuses an opened vial, to avoid cross-contamination between patients.

The maker lists five contraindications: skin disease or alteration in the area to be treated, a history of autoimmune disease or current immunotherapy, allergy to any constituent, age under 18, and pregnancy or breastfeeding.

The side effects it lists are systemic allergic reactions, such as angioedema, rash, itching, chills and fever; local inflammation, such as redness, swelling, burning, nodules, granuloma and pain; local allergic reactions such as itching; and infection, such as abscess or herpes.

DermNet notes that mesotherapy injections in general carry risks of allergic reaction, inflammation and swelling, skin infection and bruising. Tell the doctor about allergies, medical conditions, current medicines and recent procedures every time. Seek treatment immediately for severe symptoms such as difficulty breathing.