Restylane Lidocaine Thai label

The manufacturer lists three indications: facial tissue augmentation, correction of wrinkles, and lip augmentation.

The injection technique and sites are the doctor's decision for each person, and the doctor explains them at the consultation.

The manufacturer says it should not be used in people with a history of streptococcal protein allergy, since the product may contain trace amounts of this protein; in people with a history of severe allergy such as anaphylaxis; or in people allergic to lidocaine or amide-type local anaesthetics.

It must not be injected into a blood vessel, which can block the vessel and cause ischaemia or tissue death. Rare serious events such as visual disturbance or blindness, stroke-like events and skin necrosis have been reported. Changes in vision, stroke-like symptoms, whitening of the skin or unusual pain during or soon after injection mean the injection must stop at once and a doctor must be seen.

Treatment should be postponed if the area is inflamed, infected or has a tumour. People who bleed easily, or take medicines affecting platelets, thrombolytics or anticoagulants, may bruise or bleed more at the injection site. The manufacturer says safety in pregnancy, in breastfeeding and under age 18 has not been established.

After injection, bruising, redness, itching, swelling, pain or tenderness at the site can occur, usually clearing within a few days to a week, according to the manufacturer. Avoid strong sun, UV and extreme temperatures until the initial swelling and redness settle, and ask the injecting doctor before laser, chemical peels or other skin-stimulating procedures.

The manufacturer says to store it at no more than 25 °C, not to freeze it, and to keep it out of sunlight.

It is single-use and must not be re-sterilised. The syringe, needle and any remainder are discarded immediately after treatment.